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Besides that, adoptive T mobile therapies like posoleucel also intention LMP2 coupled with other latency proteins By the use of example EBNA1, reinforcing its wonderful great importance as getting a conserved and immunodominant antigen.Added benefits contain resistance to dewetting, compatibility with a hundred% aqueous cellular phases, substitute

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Therapeutic vaccine candidates making use of viral vectors encoding LMP2 have efficiently induced virus-unique CD8⁺ T cell responses in early-phase medical trials. Moreover, adoptive T mobile therapies like posoleucel also target LMP2 alongside other latency proteins such as EBNA1, reinforcing its significance like a conserved and immunodominant